Long-term potentiation, or LTP, is a process by which synaptic connections between neurons become stronger with frequent activation. LTP is thought to be a way in which the brain changes in response to experience, and thus may be an mechanism underlying learning and memory. In this video, I discuss one type of LTP: NMDA-receptor dependent LTP. I outline the mechanism underlying NMDA-receptor LTP and describe how it is thought to strengthen synaptic connections where it occurs.
Welcome to Neuroscientifically Challenged! All of the content for the site is collected on this home page, but if you're looking for specific types of content you can use the menu bar above. By clicking on Articles, you'll find links to blog articles on a variety of different neuroscience topics. The Know Your Brain link will take you to a listing of reference articles, each of which deals with a different part of the nervous system. Clicking on the 2-Minute Neuroscience Videos link will take you to an assortment of 2-minute videos that each teach you about a different aspect of neuroscience. And the Glossary contains a large selection of definitions for common neuroscience terms.