In this video I discuss the substantia nigra. I describe the two regions that make up the substantia nigra: the substantia nigra pars compacta and the substantia nigra pars reticulata. I discuss the role of the substantia nigra pars compacta in dopamine production and its contribution to the nigrostriatal pathway, one of the major dopamine pathways in the brain. I also briefly cover the role of the substantia nigra in movement and how this is disrupted by the neurodegeneration that occurs in Parkinson’s disease.
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