2-Minute Neuroscience: Periaqueductal gray

The periaqueductal gray, or PAG, is an area of gray matter that surrounds the cerebral aqueduct in the brainstem. Although it is associated with a number of functions, it is best known for its role in analgesia, or pain reduction. In this video, I discuss the PAG and the pathway by which it is thought to be able to inhibit pain signals from the spinal cord.