Opioid drugs are responsible for what many consider to be the greatest public health crisis of the 21st century in the United States. In this video, I discuss a few of the ways opioid drugs affect the brain, as well as the basis for opioid tolerance and withdrawal.
Amphetamine is a stimulant drug that is used primarily in the treatment of ADHD. In this video, I discuss some of the proposed mechanisms by which amphetamine acts on the brain to produce its stimulant effects.
Benzodiazepines are a class of drugs commonly used to treat anxiety disorders and sleep disorders. They are thought to exert their effects in the brain by acting at receptors for the neurotransmitter gamma-aminobutyric acid, or GABA. In this video, I cover the the mechanism of action for benzodiazepines and discuss how it is thought to lead to calming effects.